Thank you very much for sharing man. I love hearing about pleasantly surprised health care professionals! I know that BPC is most effective for tendon and ligament recovery, TB500 more muscular, with IGF-1 LR3 being a more general effect, and I've just been made aware of it's positive effect on osteoblastic activity. Obviously there's some tissue damage and inflammation that's beyond skelatal damage. You should put up the pic of your hardware - Iron Man!
Posts made by TimboSlice
RE: Recovering from a hip fracture
RE: Ipamorelin as a sleep aid
Mark, me and TIC remembered about 'boom' dosing Ipamorelin a few nights ago and both took 300mcg as a standalone. We both reported a very restful and full night's sleep, deep enough to keep me asleep past my usual internal alarm clock.
I might experiment with 500mcg. Actually I think I will first try 300mcg of Ipam and 100mcg of Mod-GRF to compare with my previous dose.
I seem to recall, (I'll have to have a look at some point) that boom dosing creates multiple pulses of growth hormone throughout the subsequent hours, I can't remember for how long. I might have a graph to show it, that was formerly from Dat's. Anyway!
It's very interesting because it creates a lot of 'time under tension' to use a weight training analogy, spent with high levels of growth hormone, but as it is still pulsatile, we don't get the negative effects of prolonged, elevated levels of growth hormone - one of which is a more female GH release pattern.
Keen to find out how you get on mate.
Carbless Post-Workout and Peptides
I'm going to put this here until we possibly have another sub forum for Nutritional strategies, but I wanted to share and stoke discussion on carbless PWO, a method of eating whereby you eat carbohydrates in the hours leading to your workout, and then simply omit carbohydrates for around 5 or more hours after you have exercised.
The idea behind is that as glycogen is the preferred source of fuel for the brain, after you deplete glycogen stores through exercise, the body will look to save what is left and look to other sources of fuel, i.e fat, as long as you have sufficient amino acids in the pool. Contrary to popular belief, grown through a lot of repetition about the importance of 'replenishing glycogen' post workout. There is something to be said about the role of insulin in muscle building, and it's proteosome inhibitory effect, however, all it takes to initiate muscle protein synthesis is the presence of amino acids in the blood, [in particular leucine]. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041535/)
People always talk about the amount of calories burnt during exercise but it is a very inefficient focus. Instead, think of the exercise as an event, and the subsequent state the body is then in as the time spent utilising fat as an energy source. The PWO meals usually consist of meat or eggs, and possibly some sort of greenery, a salad, cruciferous vegetables (which do have carbs in but are negligable in effect) protein basically. Naturally there will be some fat with those meals, but you don't want to go overboard here, it's a little like filling a hole with dirt only to dig it all out again.
You can eventually take in some carbs here later in the day but I don't like to go for too many - just enough to curb the cravings or possible mild hypoglycemic symptoms.
In my experience, peptides are an excellent addition to this protocol, any of those that illicit lipolysis (the releasing of fatty acids from stores, into the blood. GH Frag, Melanotan II, PT141 and the those from the GHRP family, taken preworkout. Or a combination of them (not MT and PT though imo)
Recently, I have been utilising GH Frag and Ipam around 45 minutes before I get to the gym, whether it be combat sports or weight training so that as I get deeper into my workout, I have depleted glycogen sufficiently to start to use those liberated fatty acids as fuel. You could also take more peptides post workout, which I may tend to do if I'm training in the AM but it all depends on your goals. Mine has predominately always been muscle accrual, interspersed with the odd fat loss phase just to experiment, so I usually don't bother and get more much needed (for me) calories in at this stage.
Sometimes I'll also add MTII/PT141 but I don't like to do this later on due to it's possible effect on circadian rhythms
That and I tend to go exceptionally red-faced post Melanotan injection lol.
RE: Circadian Rhythms, Peptides & Biological Efficiency
Mate, love the whole post. You not only confirmed what I'd been told, but enveloped me in knowledge And also created a few questions. firstly, what's the difference between ultradian? I'm already googling it but I thought I'd still ask for the benefit of the post, and of the forum for that matter.
I especially like the graphic. I was looking to understand what a 'barrier recovery' rate was and found this abstract trying to understand what it means - which I succeeded in doing, but it also showed me how very complicated it is!
I ask about the melanotan and it can give me a flushing effect and I prefer not to look that red-faced at work or around people because it can be quite pronounced! I may look into PT141 because I finally have a good hygienic sleep pattern and I want to keep it that way. Plus I don't want to turn really really brown like our friend
I would love to hear your thoughts on sleep hygiene by the way.
RE: Step 1 up from 'just' steroids?
Excellent post my man. I remember when I first started using Mod-GRF and GHRP-6 back on dat place, using it at 100mcg initially pre-bed but ramping up to 5-6 times a day within a day or 2 Saturation dose was have been 70mcg using the 1mcg per KG saturation dosing for me at the time. It can be difficult at this kind of schedule because of the blunting effects of food but it's not impossible.
Of course you don't have to go balls deep, in fact, I would recommend a good few pre-bed dosing only, then introduce a morning dose (this could be be semi-fasted) followed by pre-workout around 30-40min before you hit the gym IIRC. Better to milk the effects of the lower doses.
I used to like GHRP-6 because muscle gain has always been my goal, when I do train to build my physique as opposed to performance. This is due to it's action as a ghrelin mimetic, ghrelin being the 'hunger hormone'. I recall a couple of times pinning 300mcg and going to a Brazilian all you can eat BBQ Ingesting meat until you sweat isn't probably the healthist thing thing to do especially regularly mind you. Some people with different goals, avoid using GHRP-6 for this reason, opting for Ipamorelin.
I have used GH before, but I'm not comfortable really comparing the two because of my inexperience with 177 growth hormone, but I really enjoyed the effects of supplementing anabolic and androgenic steroids with judicious use of peptides. Certainly from a performance enhancing (over simply aesthetic) perspective, it has a tremendous effect. Peptides such as MGF, IGF-1, and TB500 alongside a low dose of oral steroids made a huge difference for me in strength in combat sports, both grappling and striking disciplines (we can have a discussion on the morality of PED use in sports, especially combat sports - my views are probably hypocritical, demonstrably) through direct action in/on the ring/mats and when at home resting and digesting, healing those sore bones that only fighting seems to give you.
TIC, what is the mechanism of the blunting effect that certain food groups have upon the GH secretagogues, how much of effect is it? I remember seeing a graph that showed just how badly it effected it but it's just a snapshot in my mind.
RE: Circadian Rhythms, Peptides & Biological Efficiency
Very interesting AdamZeus, I was wondering when you would bring some circadian rhythm knowledge and discussion to the party.
I know here you speak of the benefits for Ipamorelin and other GHRP's, specifically for anti-aging. Anecdotally, I have certainly experienced an improvement in the quality of my sleep when using these peptides, but do you know of any other peptides that may have a negative effect on circadian rhythm, say, Melanotan II? I have only ever used it in the morning as I think I remember TIC mentioning something. I'd love to hear more from you regarding circadian rhythms.
RE: Interesting site!
Welcome! Thanks for posting, I'm also looking forward to seeing this place develop. If you're a regular peptide user, perhaps you'd like to share some of your experiences in the ' Share Your Peptide Experiences Here ' section. It's always interesting hear how each individual has incorporated peptides into their lives, for any one or more of the multitude of benefits these amino acids can bring us.
An introduction to the Advanced Discussion
A place for people who want to take thier steroid use to the next level, by incorparating peptides. Please put some thought into your post before you submit it, so that the forum can develop into a positive discussion area fuelled by intelligent questions and thoughtful debate. Posts that have been **obviously ** made without any prior, or very little research on the posters behalf behind them may be heavily moderated, in line with the board rules
Please share your experiences so that we can get this forum going!
My healing using BPC157
I have used BPC157 to accelerate the healing process a number of times, you can read my more in-depth post over in the 'Share Your Peptide Experiences Here' forum. Can't wait to see the forum develop as I have heard alot of different people using this compound to heal injuries of varying severity, and in my own experience, there's a reason they call it wolverine juice and by they, I mean me lol.
My experience with BPC157
I have used BPC157 a number of times and with each one I always note that it is quite a remarkable peptide.
The first was to heal an intercostal stress injury sustained from a particularly gruelling Brazilian Jiujitsu session where a man literally twice my weight effectively crushed me. That night, I noticed a exceptionally intense pain when cutting cheese - a soft cheese at that - and had some relatively intense pain when breathing. Not good to say I had a tournament around 10 days away. I spot injected directly into the source of the pain, 3 times on 3 subsequent days with 375mcg. With rest (which I definitely didn't want from a competive standpoint - I'd already done too little BJJ to be even thinking about entering a competition) the pain was gone and I was able to train up until and compete in the tournament without the injury reoccuring. I also believe I generally felt less pain from the very painful sport that is BJJ.
I have injected 250mcg directly into a very, very tender and inflamed biceps tendon on numerous occasions to heal biceps tendonitis suffered from boxing. I have also done this as a premeptive measure, basically when my tendonitis isn't giving me crap and I find it very effect for this. Yesterday I injected 300mcg into my brachioradialis after a particularly hard hitting boxer (my cousin actually) injured my left arm when I was holding the pads for him. As of right now there is a level of pain maybe a 1-2 RPE compared to a 7-8 prior to administration.
Obviously, I have experimented with cuts and scrapes too, you will find it does speed the process of healing very quickly and from my experience less scar tissue - or at least less painful scar tissue. Do ensure that the wound is suitably clean else you will heal over bacteria and have to get in there and dig out the bad tissue, which I found out the hard way with my finger. Naturally, I then used BPC on it again. I have to say it can sometimes feel like it has a magical propertie, seeing skin heal over in days.
I am currently using it to heal a joint mouse that I have in my knee. 250mcg every day, or every other day directly into the inferolateral pole. It is still strapped up for another weak as a precaution but I definitely noticed a decrease in pain once I'd started using it. I also sometimes use it subQ when I can't be bothered to jab my knee haha. I surmise that this has subtle, unseen healing actions systemically.
Anyway, I thought I would kick off the experience logs. I'll probably get round to sharing my experiences with other peptides - of which there are many :